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23 Phase I Selections from the 13.1 Solicitation

(In Topic Number Order)
Akita Innovations LLC
1770 Salem Street
North Andover, MA 01845
Phone:
PI:
Topic#:
(617) 448-1588
Lawrence Hancock
CBD13-101      Awarded: 5/29/2013
Title:100% Solids Polyurethane Sequestration Coatings
Abstract:Mitigation and recovery from an attack with a chemical or biological agent remains an important challenge for the US Defense and Homeland Security. Solicitation topic CBD13- 101 envisions a multifunctional sequestration coating that once applied to a contaminated surface will sequester the contaminating agent, disclose the location of agent contamination, detoxify the agent and be removable so as to enable further clean-up and recovery operations. Akita Innovations LLC and FLIR Systems, Enzyme Technology unit (formerly Agentase) will team to develop a chemical agent sequestration coating. Akita will develop a 2 part, 100% solids polyurethane formulation which will polymerize in place to absorb and sequester the agent contaminant. FLIR will provide proven enzymatic technologies for disclosure and decontamination of chemical agents. These will be integrated into the coating formulation for in place disclosure and detoxification of chemical agents. In Phase I of this effort we will demonstrate the ability to sequester and detoxify chemical agent simulants in the coating while preventing breakthrough of the agent through the coating.

Nano Terra, Inc
50 Soldiers Field Place
Brighton, MA 02135
Phone:
PI:
Topic#:
(617) 621-8500
Xinhua Li
CBD13-101      Awarded: 5/29/2013
Title:A broad-spectrum reactive nanocomposite gel coating to sequester chemical warfare agents
Abstract:Chemical warfare agents, such as nerve and mustard agents, pose serious threats to our soldiers and civilians. An efficient barrier coating which can sequester and deactivate chemical agents is urgently needed. We propose a broad spectrum responsive nanocomposite gel coating that can irreversibly sequester and deactivate a variety of chemical agents. Our base material is a fast curing gel modified with functional groups and ions. Nanoparticles are added to tailor the reactivity and mechanical properties of the gel coating. The basic gel system will deactivate mustard agents rapidly. The functional groups will capture phosphorus-based nerve agents efficiently. The ions will accelerate the reaction against nerve agents, such as VX. A colorimetric functional group will indicate the location of contamination within the coating after deactivation. We have demonstrated that the basic gel composites form peelable gel coatings and sequester phosphorus and sulfur-containing compounds with high capture capacity. Preliminary test of the gels against 4 chemical simulants show that the gel can sequester simulants at surface loadings > 12 g/m2 with at least 95% capture efficiency. We will optimize the formulation to improve mechanical strength and capture efficiency. Testing against live agents (e.g. HD and VX) will be carried out in collaboration with Dr. Harry Salem at the Army Edgewood Chemical and Biological Center (ECBC).

TDA Research, Inc.
12345 W. 52nd Ave.
Wheat Ridge, CO 80033
Phone:
PI:
Topic#:
(303) 940-2341
Brian J. Elliott
CBD13-101      Awarded: 5/28/2013
Title:Responsive Sequestration Coating
Abstract:TDA Research, Inc. and the University of Colorado at Boulder will team together to develop a responsive sequestration coating for chemical warfare agents. The coating will be easily applied to surfaces where it will cover and contain chemical warfare agents on vehicles or other hardware known or suspected to be contaminated. A color change of the coating will indicate locations of underlying surface chemical warfare agent contamination. The agents will be contained in the coating where they will be reactively decontaminated. The coating will be robust, but easily stripped off / peeled off from the underlying surface and it will leave the vehicle / hardware undamaged and fully decontaminated. The deadly agents adsorbed by the film will also be decontaminated automatically. During the coating application process and the period when the coating is left on the vehicle, chemical agent will not be spread to other surfaces nor will it be able to evaporate through the coating. The coating process will not aerosolize the liquid agent on the surface and it will prevent the agent from evaporating to the surrounding air.

Celadon Laboratories, Inc.
6525 Belcrest Rd Suite 521
Hyattsville, MD 20782
Phone:
PI:
Topic#:
(301) 683-2118
Raymond Peterson
CBD13-102      Awarded: 5/22/2013
Title:Mobile Reader App and Internet Software for Chem-Bio Surveillance
Abstract:Chem-bio attacks are a threat to U.S. military personnel and civilians. While there exist field detection assays and associated mobile readers, it remains imperative to develop next- generation readers that are location-aware, multi-format, and cellular-capable. A compelling platform that has already led to several next-generation readers is smartphones and tablets. These devices provide key elements of a mobile reader: camera; touch screen; processor; storage; battery; firmware; operating system; and wireless connectivity. They are inexpensive and ubiquitous, and will continue to advance rapidly. During Phase I, Celadon (Hyattsville, MD) and its partner, Mobile Assay (Boulder, CO), will demonstrate that the Mobile Assay TrackerTM app for iOS and Android is superior to visual detection; that it meets or exceeds all other Phase I requirements; that it can quantify results; and that it can play an important role in chem-bio surveillance. In addition, we will configure Celadon's clinical immunoassay software, ImmunoFITTM, for Phase I assays and receipt of assay results from the Mobile Assay app. The Phase II plan is to implement all required features; configure TrackerTM and ImmunoFITTM for chem-bio assays; and enhance the system so that end-users are able to configure new assays without software programming

HOLOMIC LLC
10966 LE CONTE AVE STE 17
LOS ANGELES, CA 90024
Phone:
PI:
Topic#:
(310) 443-2070
Onur Mudanyali
CBD13-102      Awarded: 6/13/2013
Title:Global Spatiotemporal Disease Surveillance System
Abstract:We propose a next-generation reader system for Rapid Diagnostic Tests using lateral flow immunoassay cartridges. The system includes a rugged and lightweight reader that is built on a cellphone platform, a centralized data server, and bio-surveillance application software. The server communicates with readers securely over Internet, cellular and other networks. Reader design aims to provide the ultimate in accuracy, sensitivity, operability, light weight and cost, as well as the ability to read cartridges of different formats and for different indications. Using this system it will be possible to provide affordable rapid diagnostics in remote places and to collect real-time geo maps about the distribution of health conditions, spread of epidemics and biothreats.

DBC Technology Corp.
4221 Mesa St.
Torrance, CA 90505
Phone:
PI:
Topic#:
(310) 378-4156
David Cohn
CBD13-103      Awarded: 7/2/2013
Title:Advanced Real-Time Surface Contamination Sensor
Abstract:A new and promising algorithm is proposed based on hyperspectral unmixing by a sequential processor that will be further developed for data fusion to both enhance sensor sensitivity and eliminate the need for separate background interrogation, thereby allowing for fast real time detection. Sensor sensitivity will be improved by a combination of passive FTIR spectroscopy, and active thermal imaging, with pulsed illumination from an advanced, compact CO2 laser with proven tunability over 120 isotopic wavelengths. The objectives of the Phase I program are to prove the essential elements of the advanced algorithm supported by acquisition of new field data and to develop an integrated sensor architecture based on the results. The new active/passive sensor will have the capability to detect surface contaminants, airborne biological particles, and chemical vapor and aerosol agents making possible detection of a large number of agent types with a single sensor.

Physical Sciences Inc.
20 New England Business Center
Andover, MA 01810
Phone:
PI:
Topic#:
(978) 689-0003
Peter R. Seem
CBD13-103      Awarded: 8/9/2013
Title:Active-Passive Fusion for Surface Contamination Detection
Abstract:Physical Sciences Inc. (PSI) proposes to develop a sensor system based on an innovative approach for liquid contaminant detection and identification on operationally-relevant surfaces. The proposed system will provide a sensitive (1 mg/m2 objective, 500 mg/m2 threshold), stand-off (< 30 m) and on-the-move capability for measuring the long-wave infrared (8 µm – 12 µm) signatures of low vapor pressure chemical warfare agents (Mustard, VX), toxic industrial chemicals (TIC), and non-traditional agents (NTA). The proposed hardware and algorithm package combines the improved signal strength and sensitivity of active backscatter LIDAR with the broad-applicability and wavelength-selectivity of passive hyperspectral detection. Through the development of a system model and laboratory breadboard hardware in Phase I, PSI will demonstrate the feasibility of combined active-passive hardware, the expected sensitivity of the technique, and a framework for active- passive fusion algorithms. A Phase II effort will produce a TRL 5 device able to operate under relevant conditions (day/night, clear/cloudy skies) and acquire full-scene active and passive data with a ground pixel area of 50cm x 50cm at a rate sufficient for 10 mph on-the- move acquisition.

Brimrose Technology Corporation
P.O. Box 616 19 Loveton Circle
Sparks, MD 21152
Phone:
PI:
Topic#:
(410) 472-2600
Jolanta I. Soos
CBD13-104      Awarded: 9/1/2013
Title:AOTF Based Spectro-Polarimetric Imaging System For Stand Off Chemical Detection
Abstract:We propose an acousto-optic tunable filter (AOTF) spectropolarimetric imaging system for enhanced standoff chemical detection in the Long Wave Infrared (LWIR) wavelength region. The AOTF has no moving parts, making it a rugged and reliable device, and it provides polarimetric imaging capabilities, which enhances its chemical detection capabilities. We have been actively researching suitable materials for LWIR AOTF imaging systems for several years. All of our prior research on LWIR materials will be leveraged and utilized during the proposed work. We will optimize the device fabrication techniques that are needed to build the AOTF using mercurous halide materials. We will investigate the technique of apodization in the design of the AOTF device to reduce the detrimental effects of the sidelobes in the passband. The proposed spectral imaging system will have polarimetric imaging capabilities. Thus, the stand-off capabilities for chemical detection and tracking will be significantly enhanced from the polarization information. In Phase I of this work we will develop and design an AOTF spectral polarimetric imaging system that uses an LWIR focal plane array as the detector. The designed system will be fully built and demonstrated in Phase II of this project.

DRS Scientific
300 Oak Lake Road
New Kensington, PA 15068
Phone:
PI:
Topic#:
(724) 337-6070
Dennis Suhre
CBD13-104      Awarded: 9/7/2013
Title:AOTF-based Spectral Imaging for Enhanced Stand-off Chemical Detection
Abstract:DRS Scientific proposes a new type of Acousto-Optic Tuned Filter (AOTF) polarimetric hyperspectral imager that is compact, rugged, and inexpensive, has no moving parts, is free of optical aberrations, and is fast and sensitive. It will cover 8-12 mm with 8 cm-1 spectral resolution or finer, and will have mFlick sensitivity with a cooled camera, and <50 mflick with an uncooled camera. The germanium AOTF will provides low cost and simplicity, a large optical aperture, nontoxic materials, and easy fabrication. The AOTF will fit directly in front of the camera, without the need for coupling optics. This will reduce optical losses and emission along with cost, and allow for a compact sensor that can be handheld. The remainder of the system is electronics and software.

Brimrose Technology Corporation
P.O. Box 616 19 Loveton Circle
Sparks, MD 21152
Phone:
PI:
Topic#:
(410) 472-2600
Sudhir B. Trivedi
CBD13-105      Awarded: 9/3/2013
Title:Development Of Low Cost Infrared Focal Plane Array For Passive Chemical Detection Using Colloidal Quantum Dots
Abstract:We propose to develop low cost LWIR FPAs using colloidal quantum dots (CQDs) of II-VI semi-metallic compounds. Brimrose has experience in the area of II-VI semiconductor QD synthesis and LWIR detector fabrication using narrow band gap semiconductor materials. Research Triangle Institute (RTI) in NC has experience in building FPAs using CQDs, and to the best of our knowledge is the only institute that has done this. HgTe QDs are currently limited to detection up to mid-IR wavelengths, while detection in the LWIR 8 to 12 mm range is desired for standoff chemical detection. Growth and characterization of HgTe CQDs under various conditions (temperature, concentrations, ligands, precursors, and procedures) will be done to determine the optimal parameters. We will develop reliable fabrication techniques for the production of HgTe CQDs, and methods to extend the capabilities into the LWIR range will be examined. Also, the design and road map to fabricate an LWIR FPA based on CQDs will be developed. In addition, we will explore the HgSeTe alloy system, as we feel that CDQs of this material have potential as a good LWIR detector material.

Sivananthan Laboratories, Inc.
590 Territorial Drive, Suite H
Bolingbrook, IL 60440
Phone:
PI:
Topic#:
(630) 226-0080
Christopher Anton
CBD13-105      Awarded: 7/23/2013
Title:A Low-Cost, High-Performance Colloidal Quantum Dot LWIR FPA for Hyperspectral Imaging
Abstract:The primary goal of this proposed work is to develop a long wave infrared (LWIR) colloidal quantum dot (CQD)-based focal plane array (FPA) in order to significantly reduce the cost of LWIR hyperspectral imagers. In order to realize this goal, it will first be necessary to successfully fabricate and demonstrate the performance of novel LWIR HgTe CQD detector arrays. This will be accomplished through a collaboration between the Episensors Technologies team and Prof. Guyot-Sionnest’s group at the University of Chicago. The Episensors team will leverage its extensive experience in nanotechnology, infrared technologies, device design and fabrication to develop and test detector arrays utilizing HgTe CQD films as the IR absorber material. The Guyot-Sionnest group will apply their substantial expertise to develop synthesis methods for generating CQDs with good optical absorption and electrical properties in the 8-12 micron range. The LWIR CQD detector arrays will be fabricated and tested by the Episensors team. This synergistic effort will provide a high probably of success by utilizing both the chemical synthesis experience of the Guyot-Sionnest group and the IR device experience of the Episensors team.

AktiVax, Inc.
12635 E. Montview Blvd.
Aurora, CO 80045
Phone:
PI:
Topic#:
(303) 548-7054
Amir Genosar
CBD13-106      Awarded: 5/1/2013
Title:ARCH Technology for a Simple, Resilient, and Cost-Effective Auto- Injector
Abstract:A prefilled auto-injector device for storing a beneficial agent in a dry and stable format alongside a diluent, and automatically delivering the beneficial agent to a patient after reconstitution. The device comprises an automatic needle insertion mechanism and automatic needle retraction mechanism and is safe and disabled after use. The primary drug container of the auto-injector is made from high barrier foil material providing absolute barrier to moisture, oxygen and light. During shelf-life the drug is exposed to a single and safe contact material avoiding interaction with glass, silicone and rubbers that can have adverse drug stability effects. Injection is accomplished by applying external gas pressure to the foil package causing it to collapse and deliver the beneficial agent. A proprietary filling method allows filling pre-made sterile and sealed packages substantially reducing fill-finish operations and costs, and minimizing the cleanroom footprint required for manufacturing. The device is highly versatile and can be amended to a range of payloads in terms of drug volume and a number of constituents that need to be mixed; as well as the needle characteristics. The auto-injector is compact, low cost, and simple to operate.

Creare Inc.
P.O. Box 71
Hanover, NH 03755
Phone:
PI:
Topic#:
(603) 643-3800
Michael D. Jaeger
CBD13-106      Awarded: 5/1/2013
Title:A Miniature Autoinjector for Multicomponent Drugs and Vaccines
Abstract:Chemical, biological, or toxin attacks in military and civilian settings are a serious and growing concern. Standard first aid for exposure to many chemical warfare agents and toxins includes the immediate administration of relevant antidotes using an autoinjector. When an attack occurs, prefilled autoinjectors must be immediately available and thus highly portable, and they must be suitable for use by nonmedical personnel. Similarly, rapid distribution and administration of targeted vaccines is critical during a biological outbreak. Storage of drug formulations as separate components within the injector (e.g., a dry medication and a diluent) can significantly extend the shelf life of many medications. Creare proposes to develop a novel miniaturized autoinjector that automatically mixes two or more pre-filled components immediately prior to injection. The drug storage and reconstitution method is based on Creare’s recently patented technology for disposable, pre-filled drug cartridges and is applicable to single-component, dry/wet, liquid/liquid, and multicomponent combinations. In Phase I, we will develop preliminary autoinjector designs and perform laboratory tests of key actuator functions to illustrate the device form and feasibility. In the Option phase, we will develop detailed designs of the actuator mechanisms, and in Phase II we will design, produce, and test prototype autoinjector devices.

Physical Optics Corporation
Photonic Systems Division 1845 West 205th Street
Torrance, CA 90501
Phone:
PI:
Topic#:
(310) 320-3088
Gregory Zeltser
CBD13-106      Awarded: 5/1/2013
Title:Microfluidic Pneumatic Autoinjector Platform
Abstract:To address the U.S. CBD need for novel autoinjector technology that provides the warfighter with a compact, field-ready, cost-effective platform for long-term storage of any given CBT antidote that does not present a significant logistical burden, Physical Optics Corporation (POC) proposes to develop a Microfluidic Pneumatic Autoinjector (MPA) platform. The MPA will provide an innovative universal drug delivery platform that can provide long-term storage for next-generation CBT antidotes that is compact, lightweight, and robust for field use and enables autoinjection of wet-dry formulations in addition to single-component and multi-component wet formulations. The key components of the MPA include a novel design of the autoinjector and safety guards. These innovations will allow military personnel to self- or buddy-autoinject antidotes in full chem/bio protection gear. In Phase I, POC will demonstrate the feasibility of the MPA concept by developing a prototype that will meet the CBD performance metrics. POC plans to finalize the overall device design and manufacture and demonstrate the prototypes of the drug delivery system in Phase II. Also, POC will demonstrate to the DoD how this device is consistent with FDA guidelines and could be approved for drug injection via the 510(k) route.

AVRYGEN CORPORATION
1364 Madera Wy
Millbrae, CA 94030
Phone:
PI:
Topic#:
(415) 600-5937
Randal Goomer
CBD13-107      Awarded: 5/1/2013
Title:Novel physiological depot formulations for long-term butyrylcholinesterase delivery
Abstract:Oraganophosphorus poisons are potent nerve agents that function by inhibiting the action of acetylcholinestrase in nerve cells. Of these, G-class nerve agents including: Taubin, Soman and Saurin, and, V class agents such as VX represent a significant threat to US military personnel. Human plasma enzyme, Butyrylcholinesterase detoxifies organophosphates by making a covalent bond with them at stoichiometric ratios. The organophosphate nerve agents and butyrylcholinesterase are both inactivated in the bonding process; this inactivation of butyrylcholinesterase has no physiologically or psychologically adverse effects. Military operational requirements for certain types of missions make it impractical for health care providers to administer repeated intravenous doses of Butyrylcholinesterase in order to maintain a sufficiently high plasma concentration to afford protection over the duration of a mission. The ability to deliver and maintain sufficiently high concentration of Butyrylcholinesterase in the blood without repeated dosing is a capability that would enhance the operational utility of BuChE as a prophylactic, particularly in support of extended-duration missions. The goal of this proposal is to develop novel sustained-release formulation to deliver human plasma derived butyrylcholinesterase into blood circulation in order to maintain elevated HuBuChE concentrations of 80µg/mL for at least 10 days.

Luna Innovations Incorporated
1 Riverside Circle Suite 400
Roanoke, VA 24016
Phone:
PI:
Topic#:
(434) 483-4234
Zhiguo Zhou
CBD13-107      Awarded: 5/1/2013
Title:Microhydrogel Depot for Sustained Delivery of Prophylactic Bioscavenger
Abstract:Neurotoxic organophosphorus (OP) agents (e.g. sarin, soman, VX and tabun) were developed initially as pesticides and adapted for chemical warfare. OP agents are fast acting and lethal at even very low doses. Countering the threat of intoxication by OP nerve agents is an important mission for homeland security. Currently, the most promising strategy to counter OP intoxication is to scavenge the agents using injectable butyrylcholinesterase. BuChE has low substrate specificity and thus may offer a broad spectrum protection against OP agents by irreversible binding to the toxins. Human plasma-derived BuChE is effective but it is difficult to produce large quantities. Recombinant BuChE lack the necessary stability and extended circulation over sufficient periods to provide adequate prophylaxis while minimizing the need for repeated administration. Luna proposes to develop a microhydrogel- based physiological depot for long-term delivery of recombinant BuChE at proper release rates. The intramuscularly injectable depot will be able to maintain BuChE plasma concentration that is effective to bioscavenger OP agents for multiple weeks. Phase I will demonstrate the technical feasibility using in vitro assays assisted by computational modeling and Phase II will demonstrate the depot performance in appropriate animal models in preparation of IND filing.

Qrono Inc
4551 Forbes Ave Ste. 200
Pittsburgh, PA 15213
Phone:
PI:
Topic#:
(412) 709-1659
Sam Rothstein
CBD13-107      Awarded: 5/1/2013
Title:Development of a long-acting, injectable controlled release butyrylcholinesterase formulation using predictive modeling.
Abstract:Elevated levels of human butyrylcholinesterase (BuChE) confer protection from chemical warfare nerve agents and other organophosphorous chemicals. As a prophylactic, the key to enabling this protection is the ability to maintain elevated concentrations of BuChE in the plasma for days or weeks. Thus far, plasma-derived and PEGylated recombinant forms of BuChE have been tested in humans. However, both have fallen short of providing cost- effective protection in scenarios where repeated intravenous administration by a health care worker is impractical. Qrono proposes to meet the need for an organophosphorous prophylaxis with custom developed, injectable microparticles that will sustain BuChE delivery for 10 days. In Phase I, Qrono will optimize the design of BuChE containing microparticles using its proprietary formulation design software, test their in vitro release and simulate their pharmacokinetics for animal models and humans. Qrono’s unique computational approach to formulation development provides greater efficiency and accuracy in the design of depot medications than the industry standard experiment-driven methods. In Phases II and III Qrono will test the pharmacokinetics and prophylactic capabilities of its BuChE formulation with nerve agent challenge studies in animal models and then pursue commercialization through clinical trials.

Active Spectrum, Inc.
1191 Chess Dr., Suite F
Foster City, CA 94404
Phone:
PI:
Topic#:
(650) 212-2625
James White
CBD13-108      Awarded: 5/1/2013
Title:Rapid biodosimetry for accurate assessment of individual radiation exposure levels
Abstract:A novel high-sensitivity biodosimeter technology is proposed that can perform rapid, non- invasive measurement radiation biomarkers in solid human tissues such as fingernails and teeth.

Radiation Monitoring Devices, Inc.
44 Hunt Street
Watertown, MA 02472
Phone:
PI:
Topic#:
(617) 668-6800
Richard Myers
CBD13-108      Awarded: 5/1/2013
Title:Rapid biodosimetry for accurate assessment of individual radiation exposure levels
Abstract:In the event of an intentional or accidental release of ionizing radiation, it will be critical to have rapid triage assessment tools to evaluate the health of mission-critical personnel and to make effective use of available medical and emergency resources. However, assessment of whole body radiation dosage is challenging and established methods rely on visual manifestations, blood sampling and sophisticated laboratory tests that require multiple days for accurate analysis. To overcome the challenges of measuring whole body radiation exposure, Radiation Monitoring Devices, Inc. (RMD) will seek to design and assemble a field-ready biodosimeter for triage assessment of warfighters based on a simple optical method. The instrument will utilize the physiological changes caused by radiation injury as biomarkers for assessing whole-body exposure. In combination with data analysis, it offers the promise of rapid and non-invasive screening of large, diverse populations. The exploratory research performed under this grant will validate the dose assessment at time points less than 24 hours following controlled gamma-ray radiation exposure in living rat models. Information from these studies will be used to guide the design of a field-ready instrument for consistent and real-time whole body ionizing radiation dose measurements in humans.

Creare Inc.
P.O. Box 71
Hanover, NH 03755
Phone:
PI:
Topic#:
(603) 643-3800
Michael D. Jaeger
CBD13-109      Awarded: 5/17/2013
Title:Hermetic Seals for Chemical/Biological Protective Garments
Abstract:Interfaces on existing military chemical/biological protection garments are not designed to fully eliminate air gaps at fabric folds, fabric surfaces, or hook-and-loop closures, and thus do not provide a hermetic barrier against exposure. Creare proposes to develop a hermetic garment closure system that seals gaps at interfaces and provides high connection strength between two cloth articles as well as between cloth and smooth surfaces, such as for garment interfaces to rubber gloves, boots, and respirator seals. Our closure system employs a novel gasket approach that fills voids and provides enhanced adhesion and sealing to surfaces with micrometer-scale roughness. In Phase I, we will develop preliminary prototype gasket materials and closures and measure their sealing properties and mechanical strength to demonstrate the feasibility of the closure sealing approach. In the Option phase, we will improve our closure designs for manufacturability and integration with existing military chemical/biological protective garments. In Phase II, we will refine the fabrication methods for our gasket materials and produce and test prototypical closure systems.

nanoGriptech, Inc.
91 43rd St., Suite 200
Pittsburgh, PA 15201
Phone:
PI:
Topic#:
(412) 224-2136
Paul Glass
CBD13-109      Awarded: 5/15/2013
Title:Microfiber-Based Closures with Hermetic Sealing for Chem Bio Protective Garments
Abstract:Hook and loop closures in Army uniforms have been identified as the critical sources of leaks in protective clothing/equipment, which limits the overall protective capability of the ensemble. New closure systems capable of providing both the shear and peel strengths demonstrated by hook and loop systems as well as hermetic sealing against any vapor permeation across the closure need to be developed to address this shortfall to reduce the dangers of Warfighter exposure to Chemical or Biological Agents. In this proposal, we explore developing and optimizing new closure systems which achieve the same range of peel and lap shear strength performance as control hook and loop closures while demonstrating several magnitude order better resistance to vapor permeation such systems. This will be accomplished through a new closure system proposed to be based on polymer microfiber adhesives inspired by the foot-hairs found on geckos. The proposal describes a methodology to design, fabricate, and evaluate these closure systems, leveraging previous research team experience in both bio-inspired micropatterned closure development and incorporation of these materials into systems with hermetic sealing requirements.

ICET, Inc.
916 Pleasant St., Unit 12
Norwood, MA 02062
Phone:
PI:
Topic#:
(781) 769-6064
Shantha Sarangapani
CBD13-110      Awarded: 5/20/2013
Title:Self-Healing Shape Memory Polymer Coatings for Chemical/Biological Protective Clothing
Abstract:The ultimate goal is to develop coatings to self-seal or heal a textile material. Soldiers’ personal safety is compromised when CB protective uniforms become torn. This project aims to achieve this objective by coating or laminating a shape memory elastomeric polymer composite thin film with CB protective and excellent self sealing capability to an existing soldier garment fabric material. The potential mechanisms of passive and active self repair are presented. The healing process is anticipated to be enhanced by the shape memory properties and the continuous release of novel nanosealing agents from the membrane. The materials are robust thermally and environmentally to undergo industrial processing and field use. The Phase I effort will develop and screen formulations comprising an innovative stabilized nanoparticles containing CBW agent neutralizers, uniformly dispersed in a moisture vapor breathable shape memory polymer (SMP) matrix. This will be followed by the fabrication of a proof-of concept SMP material incorporated with the further down selected stabilized nanoparticles eventually as a free membrane or coated onto to a fabric. The highly moisture breathable, tear resistant elastomeric SMP liner releases agents when torn or cut to form an instantaneous flexible but tough rubbery barrier nanocomposite thus allowing shape recovery and self-repair. The coated fabric will be tested and demonstrated for the key criteria of establishing the sealing mechanism and performance . The CWA simulant and actual agent permeation will be carried out by the proposing firm and an Army certified laboratory on both the intact and self-sealed materials. The outcomes/ deliverable are first time data on the proof of concept Phase I in situ self sealing mechanisms for an ultra thin CB protective liner material and delivery of representative samples of known compositions. The Phase I option will demonstrate the more detailed self-sealing performance and active barrier properties of the prototype liner material made from a small industrial pilot trial.

TRITON SYSTEMS, INC.
200 TURNPIKE ROAD
CHELMSFORD, MA 01824
Phone:
PI:
Topic#:
(978) 250-4200
Apoorva Shah
CBD13-110      Awarded: 6/1/2013
Title:Self-Healing Shape Memory Polymer Based Coatings for Protective Garments (1001-966)
Abstract:Current CB garment systems such as Joint Services Lightweight Integrated Suit technology (JSLIST) and Joint Service Lightweight Integrated Suit Technology (JSLIST) Chemical Biological Coverall for combat vehicle crewmen (JC3) use a layer of absorptive carbon and selectively permeable membranes respectively offering protection against chemical and biological threats. It is not uncommon for garments to be torn/cut in the field during critical mission operation, compromising the protective capability of the ensemble. Typical field repair methods involve patching tears in the field, which is temporary, not completely effective and time consuming, further limiting mission capability. Triton proposes to develop novel coatings with the ability to autonomously repair tears/cuts in the CB protective garments. Since the proposed coating system is expected to be a next-to- skin application, the proposed effort will focus on chemistries that pose no health issues when selected materials are exposed to humans. It is expected that the coating will be applied/dispersed through the fabric layer of the protective ensemble as a conformal coating around the textile fibers or a fine non-woven mat. The target will be to add as little material as required to the ensemble in order to have minimal negative impact of garment weight, air permeability and comfort.